One of the chosen projects, called PneumoWave ALERT, pairs a chest-worn sensor that monitors breathing to a mobile device that sends out an immediate alert to nearby antidote carriers and emergency services if an overdose is detected, helping people get potentially life-saving treatment as soon as possible.
Another study will look at using virtual reality to help people overcome their triggers for cocaine addiction. People will be assessed using watch-like devices to determine which cues in their environment lead to a drug craving, by measuring physical changes to the body. Virtual reality will then be used to create realistic situations to repeatedly expose people to triggers in a safe environment. Previous research shows cue exposure treatment can significantly reduce the level of craving and relapse among alcoholics, but it has not yet been fully explored for people experiencing a cocaine addiction until now.
Minister for public health and prevention, Andrew Gwynne, said: ‘We're determined to harness the full potential of cutting-edge technology to save thousands of lives across the country. I want the UK to lead the way in championing innovation to end the harmful effects of addiction.'
The research is being funded through the Addiction Healthcare Goals programme, which is run by the Office for Life Sciences (OLS). Around £12m has been awarded to 11 projects across eight organisations in the UK. The projects were selected as part of the Reducing Drug Deaths Challenge and the NIHR i4i Addiction: Innovation for Treatment and Recovery Awards, which are being run in partnership with the Scottish government and National Institute for Health and Care Research (NIHR).
The funding will also support research to improve the accessibility of the life-saving drug naloxone, which rapidly reverses heroin and opioid overdose, but is typically available as an injection or nasal spray which have limitations and cannot always be used in time. Kings College London is looking into naloxone wafers which melt in the mouth and provide rapid access to this emergency medicine and can fit easily in a wallet or purse.
Several of the projects are based in Scotland which has the highest rate of drug deaths in Europe.
These include a wristband to monitor vital signs such as blood oxygen levels, heart rate and body temperature. If an overdose is suspected, the device, named Saving Sam, will send out an alert to a trusted contact. This research is being run by the University of Edinburgh and NHS Fife.
Professor Mike Lewis, NIHR's scientific director for innovation, said: ‘Interventions, including AI, that allow management in the community need this research to validate their potential so we can implement them at scale.'